Kappa Light Chain [L1C1]
This antibody recognizes kappa light chains of human immunoglobulins, which may be useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas (1-5). The most common feature of these malignancies is the restricted expression of a single light chain class. The normal human kappa/lambda ratio is approximately 2:1. The presence of clear cut light chain restriction with a kappa/lambda ratio more than 10:1 is consistent with a malignant proliferation (2,6).
| INTENDED USE |
IVD
|
| FORMAT |
Concentrate, Predilute
|
| VOLUME |
0.1 ml, 1.0 ml, 6.0 ml
|
| SOURCE |
Mouse Monoclonal
|
| CLONE |
L1C1
|
| ISOTYPE |
IgG1
|
| ANTIGEN |
Kappa immunoglobulin light chain
|
| LOCALIZATION |
Cytoplasmic
|
| POSITIVE CONTROL |
Tonsil or bone marrow
|